We are seeking driven, creative, and entrepreneurial individuals to help shape our company. At Alpha-9, you’ll find a culture of collaboration, transparency, and innovation. We are passionate about developing new medicines to help people living with cancer, and we are looking to add to our growing team.

Our Core Values

We are:
Innovative
Driven
Agile
Tenacious

We are:
Supportive
Respectful
Inclusive
Knowledgeable

We are:
Open
Transparent
Thought Partners
Accountable

Open Positions

Associate Scientist II, III, Translational Biology

About Us:

Alpha-9 Oncology is a clinical-stage biotechnology company developing radiopharmaceuticals for solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. With a strong cash position, raised from leading healthcare investors, Alpha-9 is poised to dramatically expand its team and accelerate its pipeline.

Radiopharmaceuticals, which enable internal delivery of radiation directly to tumor sites, are emerging as an exciting new class of cancer drugs. The field has evolved dramatically in the last few years, attributable to scientific advances and recent product launches. Radiopharmaceuticals are unique in that the same molecule can be used for imaging or therapeutic purposes, allowing doctors to visualize the molecule in patients prior to administration of therapy. The drug development cycle is also much shorter and capital efficient than traditional modalities.

Position Summary

Alpha-9 Oncology is seeking an Associate Scientist, Translational Biology to join our growing team. The ideal candidate will be team oriented and have experience in providing hands-on technical support for our in vivo research programs, preferably with tumor animal models and radioactive substances. This person will be involved in, designing, conducting and analyzing in vivo research experiments with our experimental radiopharmaceuticals. The ideal candidate will have multi-tasking ability and has the willingness and flexibility to assume additional responsibilities as they come up.

Some specific duties and tasks include, but are not limited to, the following:

  • Provide consistent, high quality, compassionate care for laboratory animals
  • Perform animal monitoring and health, behavior, and welfare surveillance, along with continuous awareness of current species-specific welfare issues in accordance with Canadian Council of Animal Care guidelines. This includes animal handling, inventories and record keeping, and communications if any abnormalities are observed.
  • Perform animal handling, restraints, injections, surgery, post-operative care, blood sampling and tissue collection.
  • Contribute to experimental data generation, recording and analysis.
  • Participate in lab maintenance, order, and receipt of needed supplies.
  • Maintain clear and accurate lab records (e.g., monitoring sheets, health reports, data spreadsheets, electronic notebook)
  • Execute other tasks and provide research support as directed by the Supervisor.
  • Attend and participate in weekly meetings.

Qualifications:

  • Master’s degree or Bachelor’s degree with 2-4 years of experience in relevant discipline including experience with laboratory animals
  • 2-4 years of related industrial experience, or an equivalent combination of education and experience
  • Experience with rodent handling and in vivo experiments, with tumor models being preferred
  • Experience with lab maintenance and lab records
  • Ability to work safely in a laboratory environment.
  • Knowledge in laboratory animal standards and CCAC guidelines
  • Experience with radiopharmaceuticals preferred, but not required.
  • Observational, organizational, data management and documentation skills
  • A team-player with excellent interpersonal skills who is willing to make a real impact and accelerate the development of innovative target therapies in a fast-paced environment.

What’s in it for you:

  • Full extended health and dental benefits
  • Competitive Salary, Bonus, and Equity
  • Commuter Reimbursement
  • Group Registered Retirement Savings Plan with 5% employer match
  • 20 vacation days
  • 17 Holidays
  • 5 Sick Days
  • Long Term Disability
  • Life Insurance
  • Technology allowance
  • Impactful rewarding work

Location: Vancouver, BC

Scientist, Senior Scientist Biology

About Us:

Alpha-9 Oncology is a clinical-stage biotechnology company developing radiopharmaceuticals for solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. With a strong cash position, raised from leading healthcare investors, Alpha-9 is poised to dramatically expand its team and accelerate its pipeline.

Radiopharmaceuticals, which enable internal delivery of radiation directly to tumor sites, are emerging as an exciting new class of cancer drugs. The field has evolved dramatically in the last few years, attributable to scientific advances and recent product launches. Radiopharmaceuticals are unique in that the same molecule can be used for imaging or therapeutic purposes, allowing doctors to visualize the molecule in patients prior to administration of therapy. The drug development cycle is also much shorter and capital efficient than traditional modalities.

Position Summary

Alpha-9 is seeking a Scientist or Senior Scientist to join our Biology group within our growing organization. The ideal candidate will be team oriented and have excellent knowledge and skills in Cancer/Molecular/Cell Biology, Biochemistry, and or Pharmacology, with a proven experience in in vitro assay development for drug design. Industry experience is required and experience with radiopharmaceutical development is a plus.

Some specific duties and tasks include, but are not limited to, the following:

  • Lead, manage and execute experiments to validate pipeline targets.
  • Contribute to the in vitro expertise across pipeline targets
  • Design, validate and execute preclinical experiments to demonstrate in vitro activities as well as define mechanism of action of drug candidates.
  • Contribute to strategic plans and assays development.
  • Expertise in cell culture and in vitro assays to validate targets, screen drug candidates and determine MoA
  • Experience with target expression validation (e.g. flow cytometry, ELISA, western blot), andmolecular biology techniques (e.g., qPCR, cloning)
  • Interpret and analyze data, prepare, and review study reports, communicate project progress to internal team members and external collaborators.
  • Supervise and mentor junior staffs including Associate Scientists
  • Assist with lab management tasks such as lab safety advisory, lab inspections and inventories.
  • Perform other related duties within the Biology group as needed.

Qualifications:

  • A PhD in Cancer, Cell or Molecular Biology, Biochemistry, and/or Pharmacology with 2-5+ years of relevant post-doctoral training or industrial experience and a proven track record of scientific excellence and creativity
  • Expertise in the development, optimization and execution of assays to establish MoA, binding affinity, selectivity and potency.
  • Experience in radiopharmaceutical discovery preferred, but not required.
  • Excellent observational, organizational, data management, and documentation skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment

What’s in it for you:

  • Full extended health and dental benefits
  • Competitive Salary, Bonus, and Equity
  • Commuter Reimbursement
  • Group Registered Retirement Savings Plan with 5% employer
  • 20 vacation days
  • 17 Holidays
  • 5 Sick Days
  • Long Term Disability
  • Life Insurance
  • Technology allowance
  • Impactful rewarding work

Location: Vancouver, BC

Manager, CMC Operations

About Us

Alpha-9 Oncology is a clinical-stage biotechnology company developing radiopharmaceuticals for solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. With a strong cash position, raised from leading healthcare investors, Alpha-9 is poised to dramatically expand its team and accelerate its pipeline.

Radiopharmaceuticals, which enable internal delivery of radiation directly to tumor sites, are emerging as an exciting new class of cancer drugs. The field has evolved dramatically in the last few years, attributable to scientific advances and recent product launches. Radiopharmaceuticals are unique in that the same molecule can be used for imaging or therapeutic purposes, allowing doctors to visualize the molecule in patients prior to administration of therapy. The drug development cycle is also much shorter and capital efficient than traditional modalities.

Position Summary

Alpha-9 is seeking a Manager of CMC Operations to support CMC activities for our growing clinical-stage pipeline of radiopharmaceutical products. This person will be responsible for technical project management of activities associated with clinical stage manufacturing and will serve as a point of contact for our external contract development and manufacturing organization (CDMO) partners. We are seeking a candidate with a degree in a scientific discipline and a track record of operational as well as scientific/technical contributions in previous roles.

As a start-up organization, we value team members eager to make an impact and grow with us professionally. We are seeking an individual who enjoys multi-tasking and has the willingness and flexibility to assume additional responsibilities as assigned.

Some specific duties and tasks include, but are not limited to, the following:

  • Manage external CDMO partner and supplier relationships from initial project proposal through delivery of materials.
  • Drive execution of the CMC strategy for nonclinical and clinical programs by researching and designing experiments for radiopharmaceutical formulation development in preparation for CDMO technology transfer and validation activities.
  • Collaborate with cross-functional internal teams (Business Development, R&D, Pre-clinical, Clinical and Regulatory) to achieve CMC program goals and timelines.
  • Partner with internal R&D and CMC laboratory personnel for development of robust radiolabeling processes and clinical formulations that meet target product profiles for diagnostic and therapeutic applications.
  • Critically evaluate data, draw appropriate conclusions and develop follow-up plan of action. Ability to troubleshoot, identify unusual results and design experiments that establish root cause and/or enhance knowledge of the product being developed.
  • Develop and take ownership of short-term and long-range CMC project plans and budgets.
  • Drive review and approval of technical documents and reports by leveraging strong partnerships with internal and consultant subject matter experts (SMEs).
  • Ensure delivery of nonclinical and clinical supplies according to required timelines; maintain material inventories.
  • Proactively identify resource constraints, develop mitigation strategies, and establish contingency plans to avoid program delays.

Qualifications:

  • BS degree in a scientific discipline. Advanced degree in chemistry, biochemistry, radiochemistry, or related field is preferred.
  • Minimum of 5 years of relevant experience in pharmaceutical or biotechnology industry. Peptide manufacturing or radiopharmaceutical experience is ideal.
  • Strong communication skills, ability to build strong relationships at all levels of the organization.
  • Track record of successfully driving and managing CMC development and/or clinical supply programs.
  • Strong problem-solving and organizational skills.
  • Ability to independently identify external resources to bridge gaps and enhance our internal capabilities.

What’s in it for you

  • Competitive Salary, Bonus, and Equity
  • Medical, dental and vision insurance
  • Commuter Reimbursement
  • Retirement Plan with 3% employer match
  • 20 vacation days
  • 16 Holidays
  • 5 Sick Days
  • Short Term Disability
  • Long Term Disability
  • Life Insurance
  • Technology Allowance
  • Impactful rewarding work

Location: Boston, MA (Hybrid)

Executive Administrative Assistant

About Us

Alpha-9 Oncology is a clinical-stage biotechnology company developing radiopharmaceuticals for solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. With a strong cash position, raised from leading healthcare investors, Alpha-9 is poised to dramatically expand its team and accelerate its pipeline.

Radiopharmaceuticals, which enable internal delivery of radiation directly to tumor sites, are emerging as an exciting new class of cancer drugs. The field has evolved dramatically in the last few years, attributable to scientific advances and recent product launches. Radiopharmaceuticals are unique in that the same molecule can be used for imaging or therapeutic purposes, allowing doctors to visualize the molecule in patients prior to administration of therapy. The drug development cycle is also much shorter and capital efficient than traditional modalities.

Position Summary

Alpha-9 is seeking an Executive Assistant to support the Leadership Team to provide broad, cross-functional administrative support and partner with the other administrative staff to meet the administrative needs of the organization.  They will be responsible for handling day-to-day administrative activities while maintaining a solid understanding of the Company goals to ensure smooth execution of priorities. This position reports to the Chief Business Officer.

We are an early-stage company, so this is a highly visible and impactful role in our growing organization. The ideal candidate will be a self-starter with the desire to collaborate cross-functionally. This position requires a high degree of collaboration, multi-tasking ability, and desire to strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Act as the administrative support for the Leadership Team; partner with the LT on initiatives that ensure a high-functioning organization.
  • Manage calendars; schedule, reschedule, respond to invitations, prioritize and manage calendar priorities in concert with organizational priorities and timelines.
  • Plan, coordinate and schedule internal and external meetings.
  • Anticipate, identify and solve calendar and scheduling issues long-term calendar management planning
  • Assist with board management, including logistical planning for Board and Committee meetings, and respond to requests made by Board members and their administrative staff.
  • Plan, coordinate, book and manage travel arrangements.
  • Manage and submit expense reports, new vendor set up and other PO related tasks.
  • Demonstrate leadership, analytical thinking, organizational and communication skills.
  • Handle confidential material and information and exercise discretion.

Qualifications:

  • BS/BA degree coupled with 7 years of professional experience, with 5 years in administrative roles and a minimum of 3 years supporting senior-level executives and interfacing with the Board of Directors.
  • Ability to work independently, multitask, and adjust priorities as competing projects vie for attention.
  • Highly organized, detail-oriented, and able to work in a fast-paced environment.
  • Excellent analytical skills and demonstrated strategic and organizational agility.
  • Ability to influence key stakeholders and drive decisions and outcomes as needed.
  • Demonstrates impeccable interpersonal and communication skills across all levels, both within and external to the organization.
  • Ability to effectively collaborate to reach mutually agreeable outcomes and resolve potential conflicts.
  • Demonstrated track record of professionalism and discretion.
  • Ability to work strategically and collaboratively across departments.
  • Demonstrates initiative and resourcefulness as a self-starter.
  • Excellent writing, communication, and presentation skills.
  • Demonstrates proficiency with Microsoft Office (Excel, Outlook, PowerPoint, Word).

What’s in it for you:

  • Competitive Salary, Bonus, and Equity
  • Health, dental and vision benefits
  • Retirement Savings Plan with 3% employer match
  • 20 vacation days
  • 16 Holidays
  • 5 Sick Days
  • Commuter Reimbursement
  • Short Term Disability
  • Long Term Disability
  • Life Insurance
  • Technology allowance
  • Impactful rewarding work

Location: Boston, MA (Hybrid)

Director of Corporate Strategy

About Us

Alpha-9 Oncology is a clinical-stage biotechnology company developing radiopharmaceuticals for solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. With a strong cash position, raised from leading healthcare investors, Alpha-9 is poised to dramatically expand its team and accelerate its pipeline.

Radiopharmaceuticals, which enable internal delivery of radiation directly to tumor sites, are emerging as an exciting new class of cancer drugs. The field has evolved dramatically in the last few years, attributable to scientific advances and recent product launches. Radiopharmaceuticals are unique in that the same molecule can be used for imaging or therapeutic purposes, allowing doctors to visualize the molecule in patients prior to administration of therapy. The drug development cycle is also much shorter and capital efficient than traditional modalities.

Position Summary

Alpha-9 is seeking a Director of Corporate Strategy to act as a liaison and implementer to the CEO and CBO while partnering with the CEO and CBO on initiatives that ensure a high functioning organization. The Director of Corporate Strategy helps the Chief Executive Officer (CEO) and Chief Business Officer (CBO) work most effectively with the Leadership Team (LT) and others to deliver on our mission.  This role will scope, plan, lead and execute high priority projects; monitor progress and achievement of next steps and develop and maintain an inventory of critical projects and the corporate calendar. In addition, this role will plan, schedule and facilitate LT Meetings, track outcomes and deliverables. The role requires a highly resourceful individual with high emotional intelligence, strong analytical skills and the ability to be discrete with a commitment to confidentiality.  This position reports to the Chief Business Officer.

Some specific duties and tasks include, but are not limited to, the following:

  • Act as a liaison, sounding board, and implementer to the CEO and CBO; partner with the CEO and CBO on initiatives that ensure a high functioning organization.
  • Track high-priority initiatives for the CEO, CBO and LT and identify any obstacles; communicate initiative status, pulling in other leadership team members, as necessary.
  • Provide proactive support to the CEO and CBO through data gathering, information analyzing, and presenting considerations.
  • Maintain ongoing, regular stakeholder engagements with the leadership team to create a highly integrated organization and engage in coalition building to resolve challenges.
  • Plan, schedule and facilitate LT Meetings; prepare critical meeting agendas and send out pre-reads to attendees; capture major take-a ways, track outcomes and deliverables. and work with CBO and LT to ensure follow up and communication to a broader audience, as appropriate.
  • Ensure that LT meeting objectives are realistic, participants comprehend the level of preparation required, agenda items are prioritized, and time is appropriately allocated for discussion topics.
  • Support preparation for Board Meetings, Investor Meetings, and events.
  • Partner with program leaders, functional leaders, and administrative staff to ensure streamlined activities and the coordination and orchestration of projects or commitments directly involving the CEO and the LT.
  • Develop draft communications on behalf of the CEO and/or the LT.
  • Collaborate and partner with CEO’s Executive Assistant to remain apprised of/schedule upcoming CEO commitments.
  • Work independently and execute tasks with minimal direction, and through ambiguity.

Qualifications:

  • BS/BA degree in related discipline with 7 years or experience; MBA or advanced degree preferred coupled with 5 years professional experience in the life sciences sector strongly preferred.
  • Previous or similar experience preferred.
  • Strong ability to operate at a tactical, strategic, and operational level.
  • Excellent analytical skills and demonstrated strategic and organizational agility.
  • Proficiency in planning and project organization skills
  • Strong PowerPoint skills.

What’s in it for you:

  • Competitive Salary, Bonus, and Equity
  • Health, dental and vision benefits
  • Retirement Savings Plan with 3% employer match
  • 20 vacation days
  • 16 Holidays
  • 5 Sick Days
  • Commuter Reimbursement
  • Short Term Disability
  • Long Term Disability
  • Life Insurance
  • Technology allowance
  • Impactful rewarding work

Location: Boston, MA (Hybrid)

To apply, use the form below.

Don’t see anything that matches your experience? Email us at careers@a9oncology.com

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    Recruitment & Staffing Agencies: Alpha-9 Oncology does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Alpha-9 Oncology or its employees is strictly prohibited unless contacted directly by Alpha-9 Oncology’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Alpha-9 Oncology, and Alpha-9 Oncology will not owe any referral or other fees with respect thereto.